I38M (p.Ile38Met) variant of FLT3 (P36888)
I38M (p.Ile38Met) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
I38M (p.Ile38Met) variant details
- p.Ile38Met
- 1000Genomes rs553146018
- ExAC rs553146018
- gnomAD rs553146018
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.35
- MetaLR 0.43
- MetaSVM -0.10
- CADD 23.40
- PolyPhen-2 0.64
- SIFT 0.10
- Most common in the 1KG:GIH population (allele frequency 0.0052)
- Structural context available