I33F (p.Ile33Phe) variant of FLT3 (P36888)
I33F (p.Ile33Phe) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
I33F (p.Ile33Phe) variant details
- p.Ile33Phe
- ESP rs370661880
- ExAC rs370661880
- gnomAD rs370661880
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- REVEL 0.55
- MetaLR 0.52
- MetaSVM 0.07
- CADD 23.90
- PolyPhen-2 0.99
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available