I25V (p.Ile25Val) variant of FLT3 (P36888)
I25V (p.Ile25Val) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
I25V (p.Ile25Val) variant details
- p.Ile25Val
- Ensembl rs1017573758
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.12
- MetaLR 0.17
- MetaSVM -1.01
- CADD 5.17
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available