I21T (p.Ile21Thr) variant of FLT3 (P36888)
I21T (p.Ile21Thr) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I21T (p.Ile21Thr) variant details
- p.Ile21Thr
- gnomAD rs1360829467
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.10
- MetaLR 0.18
- MetaSVM -0.96
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.86
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available