H109R (p.His109Arg) variant of FLT3 (P36888)
H109R (p.His109Arg) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H109R (p.His109Arg) variant details
- p.His109Arg
- TOPMed rs1324707983
- gnomAD rs1324707983
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.09
- MetaLR 0.05
- MetaSVM -1.03
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available