E58Q (p.Glu58Gln) variant of FLT3 (P36888)
E58Q (p.Glu58Gln) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E58Q (p.Glu58Gln) variant details
- p.Glu58Gln
- ExAC rs746910296
- gnomAD rs746910296
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.07
- MetaLR 0.22
- MetaSVM -0.88
- CADD 10.40
- PolyPhen-2 0.02
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available