D96N (p.Asp96Asn) variant of FLT3 (P36888)
D96N (p.Asp96Asn) in FLT3 (P36888) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
D96N (p.Asp96Asn) variant details
- p.Asp96Asn
- rs1044875315
- NCI-TCGA Cosmic COSV5405
- NCI-TCGA Cosmic COSV5407
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.072
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.06
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available