D62E (p.Asp62Glu) variant of FLT3 (P36888)
D62E (p.Asp62Glu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D62E (p.Asp62Glu) variant details
- p.Asp62Glu
- 1000Genomes rs147453280
- ExAC rs147453280
- gnomAD rs147453280
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.40
- MetaLR 0.52
- MetaSVM -0.16
- CADD 22.70
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available