D29V (p.Asp29Val) variant of FLT3 (P36888)
D29V (p.Asp29Val) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
D29V (p.Asp29Val) variant details
- p.Asp29Val
- ExAC rs766620089
- gnomAD rs766620089
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.56
- MetaLR 0.36
- MetaSVM -0.30
- CADD 23.90
- PolyPhen-2 0.20
- SIFT 0.02
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available