D119Y (p.Asp119Tyr) variant of FLT3 (P36888)
D119Y (p.Asp119Tyr) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D119Y (p.Asp119Tyr) variant details
- p.Asp119Tyr
- TOPMed rs978490775
- gnomAD rs978490775
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.22
- MetaLR 0.10
- MetaSVM -0.99
- CADD 23.90
- PolyPhen-2 0.31
- SIFT 0.24
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available