C65Y (p.Cys65Tyr) variant of FLT3 (P36888)
C65Y (p.Cys65Tyr) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
C65Y (p.Cys65Tyr) variant details
- p.Cys65Tyr
- Ensembl rs2137768270
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.54
- MetaLR 0.61
- MetaSVM 0.28
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available