A78T (p.Ala78Thr) variant of FLT3 (P36888)
A78T (p.Ala78Thr) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A78T (p.Ala78Thr) variant details
- p.Ala78Thr
- ExAC rs769807030
- TOPMed rs769807030
- gnomAD rs769807030
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.14
- MetaLR 0.25
- MetaSVM -0.86
- CADD 8.24
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available