A78S (p.Ala78Ser) variant of FLT3 (P36888)
A78S (p.Ala78Ser) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A78S (p.Ala78Ser) variant details
- p.Ala78Ser
- ExAC rs769807030
- TOPMed rs769807030
- gnomAD rs769807030
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.13
- MetaLR 0.31
- MetaSVM -0.71
- CADD 7.89
- PolyPhen-2 0.05
- SIFT 0.86
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available