A78P (p.Ala78Pro) variant of FLT3 (P36888)
A78P (p.Ala78Pro) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
A78P (p.Ala78Pro) variant details
- p.Ala78Pro
- ExAC rs769807030
- TOPMed rs769807030
- gnomAD rs769807030
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.39
- MetaLR 0.22
- MetaSVM -0.93
- CADD 9.15
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available