A78D (p.Ala78Asp) variant of FLT3 (P36888)
A78D (p.Ala78Asp) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A78D (p.Ala78Asp) variant details
- p.Ala78Asp
- gnomAD rs1249272183
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.38
- MetaLR 0.38
- MetaSVM -0.42
- CADD 20.10
- PolyPhen-2 0.21
- SIFT 0.17
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available