A19V (p.Ala19Val) variant of FLT3 (P36888)
A19V (p.Ala19Val) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- ExAC rs752754459
- TOPMed rs752754459
- gnomAD rs752754459
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.13
- MetaLR 0.21
- MetaSVM -0.97
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available