K35R (p.Lys35Arg) variant of FLNC (Filamin-C)
K35R (p.Lys35Arg) in FLNC (Filamin-C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- gnomAD 7-128830741-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.29
- MetaLR 0.40
- MetaSVM -0.20
- CADD 28.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available