A10S (p.Ala10Ser) variant of FLNC (Filamin-C)
A10S (p.Ala10Ser) in FLNC (Filamin-C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- gnomAD rs1337938397
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.28
- CADD 10.50
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available