V4M (p.Val4Met) variant of F9 (Coagulation factor IX)
V4M (p.Val4Met) in F9 (Coagulation factor IX) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V4M (p.Val4Met) variant details
- p.Val4Met
- ExAC rs758078866
- TOPMed rs758078866
- gnomAD rs758078866
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.27
- MetaLR 0.36
- MetaSVM -0.63
- CADD 6.49
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the HGDP:MANDENKA population (allele frequency 0.037)
- Structural context available