M65V (p.Met65Val) variant of F9 (Coagulation factor IX)
M65V (p.Met65Val) in F9 (Coagulation factor IX) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
M65V (p.Met65Val) variant details
- p.Met65Val
- gnomAD X-139537114-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.26
- MetaLR 0.77
- MetaSVM 0.36
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available