C10R (p.Cys10Arg) variant of F7 (Coagulation factor VII)
C10R (p.Cys10Arg) in F7 (Coagulation factor VII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
C10R (p.Cys10Arg) variant details
- p.Cys10Arg
- rs756153946
- gnomAD 13-113105869-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.35
- MetaLR 0.68
- MetaSVM -0.10
- CADD 23.10
- PolyPhen-2 0.78
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available