Y148H (p.Tyr148His) variant of F5 (Coagulation factor V)
Y148H (p.Tyr148His) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
Y148H (p.Tyr148His) variant details
- p.Tyr148His
- ExAC rs771301602
- TOPMed rs771301602
- gnomAD rs771301602
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.57
- CADD 22.90
- PolyPhen-2 0.65
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available