W21S (p.Trp21Ser) variant of F5 (Coagulation factor V)
W21S (p.Trp21Ser) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
W21S (p.Trp21Ser) variant details
- p.Trp21Ser
- Ensembl rs1557937411
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.40
- CADD 19.50
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available