W21C (p.Trp21Cys) variant of F5 (Coagulation factor V)
W21C (p.Trp21Cys) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
W21C (p.Trp21Cys) variant details
- p.Trp21Cys
- gnomAD rs1251829276
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.55
- CADD 25.00
- PolyPhen-2 0.53
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available