V100F (p.Val100Phe) variant of F5 (Coagulation factor V)
V100F (p.Val100Phe) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
V100F (p.Val100Phe) variant details
- p.Val100Phe
- gnomAD rs1305895983
- Missense
- Variant Prioritization Score for Impact Estimate 0.72
- REVEL 0.88
- AlphaMissense 0.60
- MetaLR 0.64
- MetaSVM 0.58
- CADD 23.70
- PolyPhen-2 0.96
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available