Q33P (p.Gln33Pro) variant of F5 (Coagulation factor V)
Q33P (p.Gln33Pro) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
Q33P (p.Gln33Pro) variant details
- p.Gln33Pro
- ExAC rs767946672
- TOPMed rs767946672
- gnomAD rs767946672
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.73
- AlphaMissense 0.22
- MetaLR 0.03
- MetaSVM -1.07
- CADD 24.50
- PolyPhen-2 0.80
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available