P78S (p.Pro78Ser) variant of F5 (Coagulation factor V)
P78S (p.Pro78Ser) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
P78S (p.Pro78Ser) variant details
- p.Pro78Ser
- TOPMed rs1257200126
- gnomAD rs1257200126
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.62
- CADD 23.80
- PolyPhen-2 0.84
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available