P144A (p.Pro144Ala) variant of F5 (Coagulation factor V)
P144A (p.Pro144Ala) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
P144A (p.Pro144Ala) variant details
- p.Pro144Ala
- ExAC rs760604679
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.74
- CADD 23.60
- PolyPhen-2 0.67
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available