P109T (p.Pro109Thr) variant of F5 (Coagulation factor V)
P109T (p.Pro109Thr) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
P109T (p.Pro109Thr) variant details
- p.Pro109Thr
- ExAC rs545681641
- TOPMed rs545681641
- gnomAD rs545681641
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.71
- CADD 22.50
- PolyPhen-2 0.37
- SIFT 0.02
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available