L90F (p.Leu90Phe) variant of F5 (Coagulation factor V)
L90F (p.Leu90Phe) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
L90F (p.Leu90Phe) variant details
- p.Leu90Phe
- gnomAD rs1487220504
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- REVEL 0.80
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available