L31V (p.Leu31Val) variant of F5 (Coagulation factor V)
L31V (p.Leu31Val) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L31V (p.Leu31Val) variant details
- p.Leu31Val
- TOPMed rs1219409853
- gnomAD rs1219409853
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.32
- CADD 9.05
- PolyPhen-2 0.17
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available