L110V (p.Leu110Val) variant of F5 (Coagulation factor V)
L110V (p.Leu110Val) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L110V (p.Leu110Val) variant details
- p.Leu110Val
- 1000Genomes rs576928863
- ExAC rs576928863
- gnomAD rs576928863
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.32
- CADD 0.23
- PolyPhen-2 0.29
- SIFT 0.45
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available