K99T (p.Lys99Thr) variant of F5 (Coagulation factor V)
K99T (p.Lys99Thr) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
K99T (p.Lys99Thr) variant details
- p.Lys99Thr
- ExAC rs758755816
- TOPMed rs758755816
- gnomAD rs758755816
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- REVEL 0.70
- CADD 22.70
- PolyPhen-2 0.86
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available