K99N (p.Lys99Asn) variant of F5 (Coagulation factor V)
K99N (p.Lys99Asn) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K99N (p.Lys99Asn) variant details
- p.Lys99Asn
- ExAC rs746247537
- gnomAD rs746247537
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.39
- CADD 19.30
- PolyPhen-2 0.16
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available