K62R (p.Lys62Arg) variant of F5 (Coagulation factor V)
K62R (p.Lys62Arg) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
K62R (p.Lys62Arg) variant details
- p.Lys62Arg
- ExAC rs755295118
- gnomAD rs755295118
- Missense
- Variant Prioritization Score for Impact Estimate 0.707
- REVEL 0.70
- CADD 33.00
- PolyPhen-2 0.76
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available