K108R (p.Lys108Arg) variant of F5 (Coagulation factor V)
K108R (p.Lys108Arg) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
K108R (p.Lys108Arg) variant details
- p.Lys108Arg
- ExAC rs754584124
- TOPMed rs754584124
- gnomAD rs754584124
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.56
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.19
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available