G4A (p.Gly4Ala) variant of F5 (Coagulation factor V)
G4A (p.Gly4Ala) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G4A (p.Gly4Ala) variant details
- p.Gly4Ala
- gnomAD rs1162228986
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.21
- CADD 5.72
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available