G25A (p.Gly25Ala) variant of F5 (Coagulation factor V)
G25A (p.Gly25Ala) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G25A (p.Gly25Ala) variant details
- p.Gly25Ala
- TOPMed rs1365830144
- gnomAD rs1365830144
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.20
- AlphaMissense 0.99
- MetaLR 0.30
- MetaSVM -0.03
- CADD 2.12
- SIFT 0.00
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available