F2L (p.Phe2Leu) variant of F5 (Coagulation factor V)
F2L (p.Phe2Leu) in F5 (Coagulation factor V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
F2L (p.Phe2Leu) variant details
- p.Phe2Leu
- TOPMed rs1170891368
- gnomAD rs1170891368
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.14
- CADD 1.67
- PolyPhen-2 0.00
- SIFT 0.99
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available