W58R (p.Trp58Arg) variant of F13A1 (Coagulation factor XIII A chain)
W58R (p.Trp58Arg) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
W58R (p.Trp58Arg) variant details
- p.Trp58Arg
- ExAC rs754004931
- gnomAD rs754004931
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.51
- MetaLR 0.32
- MetaSVM -0.64
- CADD 20.10
- PolyPhen-2 0.04
- SIFT 0.65
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available