W131S (p.Trp131Ser) variant of F13A1 (Coagulation factor XIII A chain)
W131S (p.Trp131Ser) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data and structural context.
W131S (p.Trp131Ser) variant details
- p.Trp131Ser
- TOPMed rs932213198
- gnomAD rs932213198
- Missense
- Variant Prioritization Score for Impact Estimate 0.886
- REVEL 0.92
- MetaLR 0.95
- MetaSVM 1.10
- CADD 27.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available