V35M (p.Val35Met) variant of F13A1 (Coagulation factor XIII A chain)
V35M (p.Val35Met) in F13A1 (Coagulation factor XIII A chain) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
V35M (p.Val35Met) variant details
- p.Val35Met
- 1000Genomes rs5985
- ESP rs5985
- ExAC rs5985
- TOPMed rs5985
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.16
- MetaLR 0.14
- MetaSVM -0.95
- CADD 0.34
- PolyPhen-2 0.22
- SIFT 0.13
- EBI: Benign
- UniProt: Benign
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available