V120M (p.Val120Met) variant of F13A1 (Coagulation factor XIII A chain)
V120M (p.Val120Met) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
V120M (p.Val120Met) variant details
- p.Val120Met
- ExAC rs774094090
- gnomAD rs774094090
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- REVEL 0.48
- MetaLR 0.68
- MetaSVM 0.45
- CADD 23.10
- PolyPhen-2 0.42
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available