S90R (p.Ser90Arg) variant of F13A1 (Coagulation factor XIII A chain)
S90R (p.Ser90Arg) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S90R (p.Ser90Arg) variant details
- p.Ser90Arg
- TOPMed rs956116816
- gnomAD rs956116816
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- REVEL 0.46
- MetaLR 0.39
- MetaSVM -0.50
- CADD 23.00
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available