S90G (p.Ser90Gly) variant of F13A1 (Coagulation factor XIII A chain)
S90G (p.Ser90Gly) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S90G (p.Ser90Gly) variant details
- p.Ser90Gly
- TOPMed rs956116816
- gnomAD rs956116816
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.30
- MetaLR 0.35
- MetaSVM -0.60
- CADD 22.80
- PolyPhen-2 0.03
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available