R38W (p.Arg38Trp) variant of F13A1 (Coagulation factor XIII A chain)
R38W (p.Arg38Trp) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R38W (p.Arg38Trp) variant details
- p.Arg38Trp
- TOPMed rs1328344901
- gnomAD rs1328344901
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.63
- MetaLR 0.53
- MetaSVM 0.13
- CADD 25.00
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available