R138K (p.Arg138Lys) variant of F13A1 (Coagulation factor XIII A chain)
R138K (p.Arg138Lys) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R138K (p.Arg138Lys) variant details
- p.Arg138Lys
- 1000Genomes rs202087752
- ExAC rs202087752
- TOPMed rs202087752
- gnomAD rs202087752
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.26
- MetaLR 0.11
- MetaSVM -0.92
- CADD 3.85
- PolyPhen-2 0.00
- SIFT 0.75
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available