L99I (p.Leu99Ile) variant of F13A1 (Coagulation factor XIII A chain)
L99I (p.Leu99Ile) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L99I (p.Leu99Ile) variant details
- p.Leu99Ile
- Ensembl rs2113183947
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.23
- MetaLR 0.22
- MetaSVM -0.89
- CADD 2.62
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available