L42P (p.Leu42Pro) variant of F13A1 (Coagulation factor XIII A chain)
L42P (p.Leu42Pro) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L42P (p.Leu42Pro) variant details
- p.Leu42Pro
- ExAC rs762041584
- gnomAD rs762041584
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.26
- MetaLR 0.13
- MetaSVM -0.93
- CADD 8.80
- PolyPhen-2 0.01
- SIFT 0.29
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available