L32F (p.Leu32Phe) variant of F13A1 (Coagulation factor XIII A chain)
L32F (p.Leu32Phe) in F13A1 (Coagulation factor XIII A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L32F (p.Leu32Phe) variant details
- p.Leu32Phe
- TOPMed rs1407961299
- gnomAD rs1407961299
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.20
- MetaLR 0.20
- MetaSVM -0.87
- CADD 12.30
- PolyPhen-2 0.01
- SIFT 0.74
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available